二维Savitzky-Golay数字差分器剪切波弹性成像方法

1)医学超声关键技术国家地方联合工程实验室,广东省生物医学信息监测与超声成像重点实验室,深圳大学生物医学工程学院,广东深圳 518060; 2)深圳开立生物医疗科技股份有限公司,广东深圳 518052

生物医学工程; 医学影像; 超声成像; 剪切波弹性成像; 剪切波速度估计; 杨氏模量

A shear wave elastography method based on 2D Savitzky-Golay digital differentiator
PAN Xiaochang1, 2, FENG Naizhang2, and CHEN Siping1

PAN Xiaochang1, 2, FENG Naizhang2, and CHEN Siping11)National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, Shenzhen University, Shenzhen 518060, Guangdong Province, P.R.China2)Sonoscape Corporation, Shenzhen 518052, Guangdong Province, P.R.China

biomedical engineering; medical imaging; ultrasound imaging; shear wave elastography; shear wave speed estimation; Young's modulus

DOI: 10.3724/SP.J.1249.2018.01022

备注

提出一种新的剪切波弹性成像方法,将2D SG(Savitzky-Golay)数字差分器用于剪切波计算中,使用二维曲面拟合来近似剪切波波前到达时刻,该方法相比传统的线性回归方法不易受异常数据影响,鲁棒性更强. 通过超声弹性仿体实验评估这两种方法,比较不同尺寸下的2D SG数字差分器和线性回归的剪切波弹性图. 结果表明,在图像的横向分辨率相同的情况下,本研究方法得到的剪切波弹性图像更平滑,噪声更小,且剪切波弹性图像的信噪比和对比度噪声均比传统方法要高,表明该方法能提高剪切波弹性图像的质量.

We propose a new shear wave elastography method based on the 2D Savitzky-Golay(SG)digital differentiator in the shear wave speed estimation. The 2D SG digital differentiator utilizes two dimensional surface fitting method to obtain the arrival time of shear wave's wave-front. In comparison with the linear regression method, the 2D SG digital differentiator is not only less affected by the outlier data but also more robust. Moreover, we use the ultrasound elastic phantom experiments to evaluate the two methods and compare the shear wave elastograms obtained by the two methods. The elastograms obtained by our proposed method are smoother and have lower noise than those of linear regression method, while the lateral resolutions of images are the same. In our phantom experiment, the shear wave elastograms for our new method have higher signal-to-noise ratio(SNR)and contrast-to-noise ratio(CNR). The research shows that the new proposed method effectively improves the quality of shear wave elastogram.

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