深圳大学学报理工版

为制备高效环保仿生材料,以Na2HPO4和Ca(NO3)2·4H2O为原料,采用化学沉淀法合成羟基磷灰石粉体,将粉体超声分散在壳聚糖醋酸溶液中,通过溶液共混和磁力搅拌的方法制备羟基磷灰石-壳聚糖(hydroxyapatite-chitosan, HA-CS)悬浮液.采用旋涂法在不锈钢304基材表面涂覆HA-CS悬浮液,分别在25 ℃和37 ℃条件下干燥12 h成膜.将两种HA膜样分别通过X射线衍射、傅立叶变换红外光谱、扫描电子显微镜、X射线能量色散仪和电子拉力机进行测试.结果表明,HA-CS复合材料的拉伸强度达(69.04±1.21)MPa; 复合膜结晶度好,黏结致密,无分解,无杂质; 旋涂法能更好的使HA均匀分散在CS中,减少HA微粒的团聚和游离; 与25 ℃相比,37 ℃条件下干燥HA膜有助于HA与CS更多更好地结合,使制得的HA-CS复合膜具有优良性能.为HA-CS复合膜附着金属植入物在人体环境内成功生长提供理论参考.

Based on a chemical precipitation method, the hydroxyapatite powders were prepared using Na2HPO4 and Ca(NO3)2·4H2O as raw materials. The powders were dispersed into chitosan-acetic acid solution with the aid of continuous ultrasonic agitation to prepare hydroxyapatite-chitosan(HA-CS)suspension via solution blending and magnetic stirring. Hydroxyapatite-chitosan composite coatings were fabricated on 304-type stainless steel substrates by a spin-coating technique, then dried at 25 ℃ and 37 ℃ for 12 h, respectively. The two synthesized samples were characterized and tested by X-ray diffraction(XRD), Fourier transform infrared spectroscopy(FTIR), scanning electron microscopy(SEM), energy-dispersive X-ray spectroscopy(EDX)and electronic tensile machine. The results indicate the tensile strength of HA-CS composites reaches up to(69.04±1.21)MPa, and the coatings display good crystallinity, good adhesion, high purity and little decomposition. In addition, by means of spin-coating technique, HA could be evenly dispersed in CS and there are no aggregated or free HA particles in the coatings. The HA-CS composite coatings show better performance when drying at 37 ℃ than at 25 ℃, which is more conducive to combine interaction between HA and CS.

引言
1 实验
2 结果与讨论
3 结语

图1 HA(a)、CS(b)和不同干燥条件下 HA-CS复合膜(c、d)的XRD图<br/>Fig.1 XRD patterns of HA(a), CS(b)and HA-CS composite coatings at drying temperatures of 25 ℃(c)and 37 ℃(d)

图1 HA(a)、CS(b)和不同干燥条件下 HA-CS复合膜(c、d)的XRD图
Fig.1 XRD patterns of HA(a), CS(b)and HA-CS composite coatings at drying temperatures of 25 ℃(c)and 37 ℃(d)

图2 CS(a)、HA(b)和不同干燥条件下HA-CS复合膜的FTIR图<br/>Fig.2 FTIR spectra of CS(a), HA powders(b)and HA-CS composite coatings at different drying temperatures

图2 CS(a)、HA(b)和不同干燥条件下HA-CS复合膜的FTIR图
Fig.2 FTIR spectra of CS(a), HA powders(b)and HA-CS composite coatings at different drying temperatures

图3 不同干燥条件下HA-CS复合膜的SEM图<br/>Fig.3 SEM images of HA-CS composite coatings under different drying conditions

图3 不同干燥条件下HA-CS复合膜的SEM图
Fig.3 SEM images of HA-CS composite coatings under different drying conditions

图4 37 ℃干燥条件下HA-CS复合膜的EDX图<br/>Fig.4 EDX image of HA-CS composite coatings drying at 37 ℃

图4 37 ℃干燥条件下HA-CS复合膜的EDX图
Fig.4 EDX image of HA-CS composite coatings drying at 37 ℃

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引言

1 实验

2 结果与讨论

3 结语

期刊信息

备注

引言

1 实 验

2 结果与讨论

3 结语

期刊信息

1 实验