[1]张敏,权润爱,苏红,等.光泵连续太赫兹波在生物成像中的应用研究(英文)[J].深圳大学学报理工版,2014,31(2):160-163.[doi:10.3724/SP.J.1249.2014.02160]
 Zhang Min,Quan Runai,Su Hong,et al.Investigation of optically pumped continuous terahertz laser in biological imaging[J].Journal of Shenzhen University Science and Engineering,2014,31(2):160-163.[doi:10.3724/SP.J.1249.2014.02160]
点击复制

光泵连续太赫兹波在生物成像中的应用研究(英文)()
分享到:

《深圳大学学报理工版》[ISSN:1000-2618/CN:44-1401/N]

卷:
第31卷
期数:
2014年第2期
页码:
160-163
栏目:
光电工程
出版日期:
2014-03-20

文章信息/Info

Title:
Investigation of optically pumped continuous terahertz laser in biological imaging
文章编号:
20140208
作者:
张敏权润爱苏红胡学娟
深圳市激光工程重点实验室,深圳大学电子科学与技术学院,深圳518060
Author(s):
Zhang Min Quan Run’ai Su Hong and Hu Xuejuan
Shenzhen Key Laboratory of Laser Engineering, College of Electronics Science and Technology, Shenzhen University, Shenzhen 518060, P.R.China
关键词:
光电子与激光技术连续太赫兹波太赫兹生物样品扫描成像图像处理伪彩色
Keywords:
optoelectronics and laser engineering continuous wave terahertz terahertz bio-sample scanning imaging image processing false-color image
分类号:
TN 219
DOI:
10.3724/SP.J.1249.2014.02160
文献标志码:
A
摘要:
采用连续太赫兹激光器(SIFIR 50)作为光源对生物样品进行太赫兹成像,得到具有较高分辨率的太赫兹图像.由于生物体内部组织结构的不同,同时得到了内部明暗对比显著的图像,鉴于人眼对彩色图像更敏感的特点,对成像结果进行伪彩色图像处理,得到了较好的结果.
Abstract:
Terahertz imaging is of great potential in biological and biomedical researches for bio-sample structure analysis and pathological-tissues diagnosis. For optically pumped terahertz laser imaging, it can offer high output power, large dynamic range and high signal-to-noise ratio. In this paper, continuous wave terahertz laser (SIFIR 50) was employed for terahertz bio-sample imaging. The internal information of the sample was obtained and it confirmed the application of continuous wave terahertz imaging system. In order to make it more convenient for the naked eye to watch, false-color image processing was applied to the original terahertz images.

参考文献/References:

[1] Zhou Zekui, Zhang Tongjun, Zhang Guangxin. Science and technology of terahertz wave[J]. Process Automation Instrumentation, 2006, 27(3):1-6.(in Chinese)
周泽魁,张同军,张光新.太赫兹波科学与技术[J].自动化仪表, 2006, 27(3):1-6.
[2] Jeong Young Uk, Kazakevitch Grigori M, Cha Hyuk Jin, et al. Demonstration of a wide-band compact free electron laser to the THz imaging of bio samples[J]. Nuclear Instruments and Methods in Physics Research A, 2007,575(1/2): 58-62.
[3] Woodward R M, Cole B E, Wallace V P, et al. Terahertz pulse imaging in reflection geometry of human skin cancer and skin tissue[J]. Physics in Medicine and Biology, 2002,47(21): 3853-3863.
[4] Knobloch P, Schildknecht C, Kleine-Ostmann T, et al. Medical THz imaging: an investigation of histo-pathological samples[J]. Physics in Medicine and Biology, 2002, 47(21): 3875-3884.
[5] Hu B B, Nuss M. Imaging with terahertz waves[J]. Optics Letters, 1995, 20(16): 1716-1717.
[6] Miura Y, Kamataki A, Uzuki M, et al. Terahertz-wave spectroscopy for precise histopathological imaging of tumor and non-tumor lesions in paraffin sections[J]. The Tohoku Journal of Experimental Medicine, 2011,223(4): 291-296.
[7] Bennett D B, Taylor Z D, Tewari P, et al. Terahertz sensing in corneal tissues[J]. Journal of Biomedical Optics,2011, 16(5): 057003-1-057003-8.
[8] Sim Y C, Park J Y, Ahn K M, et al.Terahertz imaging of excised oral cancer at frozen temperature[J]. Biomedical Optics Express,2013,4(8): 1413-1421.
[9] Fan Xinmin, Zheng Yi, Wang Guanjun, et al. Two calculation methods for measuring the beam waist of Gaussian laser beam using a 90/10 knife-edge method[J]. Applied Laser, 2008, 28(2):139-141.(in Chinese)
樊心民, 郑义, 王冠军, 等. 90/10刀口法测量高斯激光光束束腰的两种计算方法[J].应用激光, 2008, 28(2):139-141.
[10] Gonzalez R C, Woods R E. Digital image processing[M]. 2nd ed. Beijing: Upper Saddle River(USA): Prentice Hall, 2007: 243-247.

相似文献/References:

[1]阮双琛,权润爱,张敏,等.反射式连续波太赫兹成像系统[J].深圳大学学报理工版,2010,27(1):6.
 RUAN Shuang-chen,QUAN Run-ai,ZHANG Min,et al.CW THz imaging constructions in reflection geometry[J].Journal of Shenzhen University Science and Engineering,2010,27(2):6.
[2]郭媛,阮双琛.含空气小孔芯光子晶体光纤的色散特性研究[J].深圳大学学报理工版,2010,27(4):386.
 GUO Yuan and RUAN Shuang-chen.Analysis on the dispersion properties of photonic crystal fiber with an air-hole defect core[J].Journal of Shenzhen University Science and Engineering,2010,27(2):386.
[3]郭春雨,阮双琛,陈祖聪,等.18.4 W皮秒光纤激光器及其全光纤化超连续谱源[J].深圳大学学报理工版,2011,28(No.3(189-282)):218.
 GUO Chun-yu,RUAN Shuang-chen,CHEN Zu-cong,et al.An all-fiber supercontinuum source pumped with a 18.4 W picosecond fiber laser[J].Journal of Shenzhen University Science and Engineering,2011,28(2):218.
[4]阮双琛,闫培光,郭春雨,等.光子晶体光纤超连续谱光源[J].深圳大学学报理工版,2011,28(No.4(283-376)):295.
 RUAN Shuang-chen,YAN Pei-guang,GUO Chun-yu,et al.Photonic crystal fiber supercontinuum source[J].Journal of Shenzhen University Science and Engineering,2011,28(2):295.
[5]成建群,阮双琛,郭春雨,等.窄线宽掺铒光子晶体光纤激光器[J].深圳大学学报理工版,2011,28(No.5(377-470)):400.
 CHENG Jian-qun,RUAN Shuang-chen,GUO Chun-yu,et al.Narrow linewidth Erbium-doped photonic crystal fiber laser[J].Journal of Shenzhen University Science and Engineering,2011,28(2):400.
[6]房鸿,马瑞龙,成建群,等.纳秒脉冲泵浦光子晶体光纤产生超连续谱[J].深圳大学学报理工版,2011,28(No.6(471-564)):523.
 FANG Hong,MA Rui-long,CHENG Jian-qun,et al.Supercontinuum generation in a photonic crystal fiber pumped by nanosecond pulses[J].Journal of Shenzhen University Science and Engineering,2011,28(2):523.
[7]杜戈果,张灵聪,赵俊清,等.主动调Q掺铥双包层光纤激光器[J].深圳大学学报理工版,2012,29(No.5(377-470)):417.[doi:10.3724/SP.J.1249.2012.05417]
 DU Ge-guo,ZHANG Ling-cong,ZHAO Jun-qing,et al.Actively Q-switched thulium-doped double-clad fiber laser[J].Journal of Shenzhen University Science and Engineering,2012,29(2):417.[doi:10.3724/SP.J.1249.2012.05417]
[8]房鸿,刘文礼,张敏,等.基于光子晶体光纤的多波长环形激光器[J].深圳大学学报理工版,2012,29(No.6(471-580)):482.[doi:10.3724/SP.J.1249.2012.06482]
 FANG Hong,LIU Wen-li,ZHANG Min,et al.Multiple-wavelength ring laser based on photonic crystal fiber[J].Journal of Shenzhen University Science and Engineering,2012,29(2):482.[doi:10.3724/SP.J.1249.2012.06482]
[9]邵英,庄飚,钱美.双折射效应和去直流检测法的MOCT模型研究[J].深圳大学学报理工版,2013,30(No.3(221-330)):221.[doi:10.3724/SP.J.1249.2013.03221]
 Shao Ying,Zhuang Biao,and Qian Mei.Modeling research of magneto-optic current transformer based on birefringence effect and deleting DC double-light detection[J].Journal of Shenzhen University Science and Engineering,2013,30(2):221.[doi:10.3724/SP.J.1249.2013.03221]
[10]郭春雨,林怀钦,阮双琛,等.连续波泵浦的高功率全光纤化超连续谱光源[J].深圳大学学报理工版,2013,30(No.4(331-440)):423.[doi:10.3724/SP.J.1249.2013.04423]
 Guo Chunyu,Lin Huaiqin,Ruan Shuangchen,et al.High-power all-fiber CW-pumped supercontinuum source[J].Journal of Shenzhen University Science and Engineering,2013,30(2):423.[doi:10.3724/SP.J.1249.2013.04423]

备注/Memo

备注/Memo:
Received:2013-09-01;Revised:2013-12-20;Accepted:2014-01-18
Foundation:Science and Technology Planning Project of Guangdong Province(2006B3733002);Shenzhen Science and Technology Research Foundation for Basic Project(JC201105170626)
Corresponding author:Senior lab master Zhang Min. E-mail: zhangmin@szu.edu.cn
Citation:Zhang Min, Quan Run’ai, Su Hong, et al. Investigation of optically pumped continuous terahertz laser in biological imaging[J]. Journal of Shenzhen University Science and Engineering, 2014, 31(2): 160-163.
基金项目:广东省科技计划资助项目(2006B3733002);深圳市科技基础研究计划资助项目(JC201105170626)
作者简介:张敏(1978-),女(汉族), 湖北省宜昌市人, 深圳大学高级实验师、博士. E-mail: zhangmin@szu.edu.cn
引文:张敏,权润爱,苏红,等. 光泵连续太赫兹波在生物成像中的应用研究[J]. 深圳大学学报理工版,2014,31(2):160-163.(英文版)
更新日期/Last Update: 2014-03-20