[1]林浩铭,陈思平,汪天富.表面波软组织黏弹性测量仿真的研究[J].深圳大学学报理工版,2013,30(No.3(221-330)):261-267.[doi:10.3724/SP.J.1249.2013.03261]
 Lin Haoming,Chen Siping,and Wang Tianfu.Simulation study on viscoelasticity measurement of soft tissue using the surface wave method[J].Journal of Shenzhen University Science and Engineering,2013,30(No.3(221-330)):261-267.[doi:10.3724/SP.J.1249.2013.03261]
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表面波软组织黏弹性测量仿真的研究()
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《深圳大学学报理工版》[ISSN:1000-2618/CN:44-1401/N]

卷:
第30卷
期数:
2013年No.3(221-330)
页码:
261-267
栏目:
电子与信息科学
出版日期:
2013-05-19

文章信息/Info

Title:
Simulation study on viscoelasticity measurement of soft tissue using the surface wave method
文章编号:
20130307
作者:
林浩铭1陈思平12汪天富2
1)浙江大学生物医学工程与仪器科学学院,杭州 310029
2)深圳大学医学院,广东省生物医学信息检测与超声成像重点实验室,深圳 518060
Author(s):
Lin Haoming1 Chen Siping12 and Wang Tianfu2
1) College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou 310029, P.R.China
2) Guangdong Key Laboratory of Biomedical Information Detection and Ultrasound Imaging, College of Medicine, Shenzhen University, Shenzhen 518060, P.R.China
关键词:
超声学表面波黏弹性有限元分析位移估计卡尔曼滤波相位估计
Keywords:
ultrasound surface wave viscoelasticity finite element analysis displacement estimation Kalman filter phase estimation
分类号:
R 318.0;R 318.6
DOI:
10.3724/SP.J.1249.2013.03261
文献标志码:
A
摘要:
基于表面波的黏弹性参数超声测量法,提出引入Zener黏弹性模型,推导Zener黏弹性组织中表面波频散速度与黏弹性参数的关系,采用有限元法建立仿真模型,记录表面波位移,结合Field Ⅱ工具包对超声黏弹性参数测量进行仿真验证.仿真模型在不同泊松比情况下, Voigt模型中剪切弹性μ和剪切黏性η的平均估计偏差分别为3.78%和1.41%,而在Zener模型中剪切弹性μ1、 μ2和剪切黏性η的平均估计偏差分别为3.76%、6.89%和4.63%.仿真估计偏差结果在可接受范围内,表明该方法用于软组织表面病灶黏弹性测量可行.
Abstract:
A surface wave viscoelastic parameters measurement method based on ultrasonic technique is proposed. A Zener viscoelasticity model is introduced and its formula relationship between surface wave dispersion velocity and viscoelastic parameters is deduced. A simulation model is also built using the finite element method, and the displacement of surface wave is recorded.The ultrasound viscoelastic parameters measurement is simulated using the Field Ⅱ toolbox.When the simulation model chooses different Poisson’s values, the average estimation biases of the shear elasticity μ and shear viscosity η for the Voigt model are 3.78% and 1.41%, respectively, whereas the average estimation biases of the shear elasticity μ1, μ2 and shear viscosity η for the Zener model are 3.76%, 6.89% and 4.63%, respectively.The simulation results of estimation biases are in acceptable range and demonstrate the feasibility of this method in the viscoelasticity measurement of surface lesion of soft tissue.

参考文献/References:

[1] Sarvazyan A P,Rudenko O V,Swanson S D,et al.Shear wave elasticity imaging: a new ultrasonic technology of medical diagnostics[J].Ultrasound in Medicine and Biology,1998,24(9):1419-1435.
[2] Zhu Ying, Shen Yuanyuan, Chen Xin,et al.Rheological properties analysis of rats liver in fibrosis stages [J]. Journal of Shenzhen University Science and Engineering,2013,30(2):216-220.(in Chinese)
朱颖,沈圆圆,陈昕,等. 大鼠肝纤维化分期的流变特性分析[J].深圳大学学报理工版. 2013, 30(2): 216-220.
[3] Rivaz H,Boctor E M,Choti M A,et al.Real-time regularized ultrasound elastography[J].IEEE Transactions on Medical Imaging,2011,30(4):928-945.
[4] Ophir J,Alam S K,Garra B,et al.Elastography:ultrasonic estimation and imaging of the elastic properties of tissues[C]// Proceedings of the Institution of Mechanical Engineers Part H:Journal of Engineering in Medicine,1999,213(3) :203-233.
[5] Lubinski M A,Emelianov S Y,O’Donnell M.Speckle tracking methods for ultrasonic elasticity imaging using short-time correlation[J].IEEE Transactions on Ultrasonics,Ferroelectrics and Frequency Control,1999, 46(1) :82-96.
[6] O’Donnell M,Skovoroda A R,Shapo B M,et al.Internal displacement and strain imaging using ultrasounic speckle tracking[J].IEEE Transactions on Ultrasonics,Ferroelectrics and Frequency Control,1994,41(3) :314-325.
[7] Nightingale K,Soo M S,Palmeri M,et al.Imaging tissue mechanical properties using impulsive acoustic radiation force[C]// IEEE International Symposium on Biomedical Imaging:Nano to Macro.[s.l.]:IEEE Press, 2004,1:41-44.
[8] Nightingale K R,Palmeri M L,Nightingale R W,et al.On the feasibility of remote palpation using acoustic radiation force[J].Journal of the Acoustical Society of America,2001,110(1) :625-634.
[9] Greenleaf J F,Urban M W,Chen S G. Measurement of tissue mechanical properties with shear wave dispersion ultrasound vibrometry (sduv)[C]// Embc:Annual International Conference of the IEEE Engineering in Medicine and Biology Society.Minneapolis (USA): [s.n.], 2009:4411-4414.
[10] Chen S G,Urban M W,Pislaru C,et al.Shearwave dispersion ultrasound vibrometry (sduv) for measuring tissue elasticity and viscosity[J].IEEE Transactions on Ultrasonics,Ferroelectrics and Frequency Control,2009,56(1):55-62.
[11] Oestreicher H L.Field and impedance of an oscillating sphere in a viscoelastic medium with an application to biophysics[J].Journal of the Acoustical Society of America,1951,23(11):707-714.
[12] Roylance D.Engineering Viscoelasticity[DB/OL].[2001-10-04].http:// ocw.mit.edu/courses/materials-sci-ence-and-engineering/3-11-mechanics-of-materials-fall-1999/modules/visco.pdf.
[13] Miller G F,Pursey H.The field and radiation impedance of mechanical radiators on the free surface of a semi-infinite isotropic solid[J].Proceedings of the Royal Society of London Series A:Mathematical Physical and Engineering Sciences,1954,223(1155):521-541.
[14] Pinton G F,Dahl J J,Trahey G E.Rapid tracking of small displacements with ultrasound[J].IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control,2006,53(6):1103-1117.
[15] Hasegawa H,Kanai H.Improving accuracy in estimation of artery-wall displacement by referring to center frequency of RF echo[J].IEEE Transactions on Ultrasonics,Ferroelectrics and Frequency Control,2006,53(1):52-63.
[16] Zheng Y, Chen S G,Tan W,et al.Detection of tissue harmonic motion induced by ultrasonic radiation force using pulse-echo ultrasound and kalman filter[J].IEEE Transactions on Ultrasonics,Ferroelectrics and Frequency Control,2007,54(2):290-300.
[17] Christensen R M.Theory of Viscoelasticity[M].New York:Dover Publications Inc,2010.
[18] Jensen J A.Simulation of advanced ultrasound systems using Field II[C]// IEEE International Symposium on Biomedical Imaging: Macro To Nano.Arlington(USA):IEEE Press,2004,1: 636-639.

相似文献/References:

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备注/Memo

备注/Memo:
Received:2012-11-05;Revised:2013-04-10;Accepted:2013-04-28
Foundation:National Natural Science Foundation of China (61031003) ;Shenzhen Science and Technology Plan Project (CXB201005240009A)
Corresponding author:Professor Chen Siping.E-mail:chensiping@szu.edu.cn
Citation:Lin Haoming,Chen Siping,Wang Tianfu.Simulation study on viscoelasticity measurement of soft tissue using the surface wave method[J]. Journal of Shenzhen University Science and Engineering, 2013, 30(3): 261-267.(in Chinese)
基金项目:国家自然科学基金资助项目(61031003);深圳市科技计划项目重大课题资助项目(CXB201005240009A)
作者简介:林浩铭(1983-),男(汉族),广东省汕头市人,浙江大学博士研究生.E-mail:linhaomail@163.com
引文:林浩铭,陈思平,汪天富.表面波软组织黏弹性测量仿真的研究[J]. 深圳大学学报理工版,2013,30(3):261-267.
更新日期/Last Update: 2013-05-19