[1]陈昕,郭燕荣,王毅,等.超声辐射力弹性成像系统研究及仿体实验[J].深圳大学学报理工版,2013,30(No.1(001-110)):54-59.[doi:10.3724/SP.J.1249.2013.01054]
 ultrasonics,radiation force elastography,shear waves,et al.Ultrasonic radiation force elastography system for measuring tissue viscoelasticity: an in vitro study on phantom and rat liver[J].Journal of Shenzhen University Science and Engineering,2013,30(No.1(001-110)):54-59.[doi:10.3724/SP.J.1249.2013.01054]
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超声辐射力弹性成像系统研究及仿体实验()
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《深圳大学学报理工版》[ISSN:1000-2618/CN:44-1401/N]

卷:
第30卷
期数:
2013年No.1(001-110)
页码:
54-59
栏目:
电子与信息科学
出版日期:
2013-01-31

文章信息/Info

Title:
Ultrasonic radiation force elastography system for measuring tissue viscoelasticity: an in vitro study on phantom and rat liver
作者:
陈昕1郭燕荣1王毅1沈圆圆1林浩铭1朱颖1郑翊2汪天富1陈思平1
1) 医学超声关键技术国家地方联合工程实验室,广东省生物医学信息检测与超声成像重点实验室,深圳大学医学院生物医学工程系, 深圳 518060
2) 美国圣克劳德州立大学电子与计算机工程系, 圣克劳德 56301,美国
Author(s):
ultrasonics; radiation force elastography; shear waves; Kalman filter; viscoelasticity; medical image
1) National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Department of Biomedical Engineering, School of Medicine, Shenzhen University, Shenzhen 518060, P.R. China
2) Department of Electrical and Computer Engineering, St.Cloud State University, St.Cloud 56301, USA
关键词:
超声学辐射力弹性成像剪切波卡尔曼滤波黏弹性医学图像
Keywords:
ultrasonics radiation force elastography shear waves Kalman filter viscoelasticity medical image
分类号:
R 318.01;R 445.1
DOI:
10.3724/SP.J.1249.2013.01054
文献标志码:
A
摘要:
用于进行超声辐射力弹性成像研究的系统主要包含激励与检测两个部分.激励探头在介质中产生聚焦声辐射力,激励组织振动并产生剪切波的传播,检测探头通过脉冲回波方式对剪切波信号进行检测.回波经放大、滤波和采样后,对离线数据进行卡尔曼滤波获得剪切波的相位,以此计算剪切波速度并得到介质的黏弹性系数.基于该系统进行了初步的琼脂仿体和离体大鼠肝脏仿体实验,结果显示通过该系统能有效检测仿体的黏弹性系数,可为后续研究提供系统支持.
Abstract:
The system of ultrasonic radiation force elastography mainly consists of excitation component and detection component. The excitation transducer was focused on one location within the medium to generate harmonic vibration and shear wave propagation, and the detection transducer was applied to detect the shear wave at other locations along the propagation path of shear wave using pulse-echo method. The received echoes were amplified, filtered, digitized and then processed by Kalman filter to estimate the vibration phase. According to the phase changes between different propagation locations, the shear wave speeds were estimated, and ultimately, tissue elasticity and viscosity moduli were calculated. Preliminary studies on agar phantom and in vitro healthy rat liver
verify the operability and measurement accuracy of the entire system. The results show that the system can effectively measure the viscoelasticity of phantom and rat liver, which will provide good support for our subsequent studies.

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备注/Memo

备注/Memo:
Received:2012-05-08;Revised:2012-12-14;Accepted:2012-12-27
Foundation:National Natural Science Foundation of China (61031003, 81271651)
Corresponding author:Professor Chen Siping. Email: chensiping@szu.edu.cn
Citation:Chen Xin,Guo Yanrong,Wang Yi,et al.Ultrasonic radiation force elastography system for measuring tissue viscoelasticity: an in vitro study on phantom and rat liver[J]. Journal of Shenzhen University Science and Engineering, 2013, 30(1): 54-59.(in Chinese)
基金项目:国家自然科学基金资助项目(61031003,81271651)
作者简介:陈昕(1975-),男(汉族),深圳大学副教授、博士.E-mail: chenxin@szu.edu.cn
引文:陈昕,郭燕荣,王毅,等.超声辐射力弹性成像系统研究及仿体实验[J]. 深圳大学学报理工版,2013,30(1):54-59.
更新日期/Last Update: 2013-01-20